CORI Clinical Studies Update:
Expanding Patient Recruitment

October 7, 2004 - The Clinical Outcomes Research Initiative (CORI) is expanding recruitment for the "Colonoscopic surveillance in patients with adenomas” study. This study is funded by an NIDDK grant awarded to Oregon Health & Science University. The goal of the study is to determine which patients have the greatest risk of developing colorectal cancer (CRC) based on criteria such as family history of CRC, lifestyle habits, overall health and characteristics such as the size and location of the polyp.

Over the last two years, CORI has recruited nearly 2,000 patients for this research and is currently extending an invitation to participate in this study to all of the sites in the CORI consortium.

CORI promotes site participation by conducting all patient recruitment, working with local or central Institutional Review Boards, and providing the follow-up calls needed to collect research data.

CORI’s clinical trial services augment the extensive data in the National Endoscopic Database. In addition to these services, CORI’s engineers may develop new technologies to collect research data more effectively.

CORI’s active clinical research projects include:

• Colonoscopic surveillance in patients with adenomas
• Multi-center study of natural history for Barrett’s esophagus
• Complications of colonoscopy performed on asymptomatic patients
• Use of the CORI database to determine hemorrhagic and thrombotic adverse events in the peri-endoscopic period

If your site would like to participate in any of these studies, propose a new research protocol, or you would like further information, please contact:

LeAnn Michaels
Clinical Studies Manager
Clinical Outcomes Research Initiative
503.494.4706
michaell@ohsu.edu